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News

Latest

🔥 Preprint

New preprint: a brain signature of pain relief (PARES)

“Beyond pain: a brain-based biomarker predicts individual pain relief” by Jialin Li et al. — a task-fMRI signature that captures both pain exacerbation and relief, validated in chronic back pain.

August 25th 2026

🔥 Preprint

August 8th 2026

🎉 New paper

July 17th 2026

🔥 Preprint

May 14th 2026

🎉 New paper

SFB 1280 paper in Nature Communications: predicting fear & cognitive extinction

“Predicting individual differences of fear and cognitive learning and extinction” by Gomes, Bach, Razi, …, Spisak, Axmacher et al.

April 23rd 2026

🔥 Preprint

New preprint: cerebellar contributions to placebo analgesia

“Cerebellar activation in human placebo analgesia: Bridging findings from mice to humans” by Zhenjiang Wei et al. — cross-species evidence that the cerebellum is engaged during placebo analgesia, linking rodent findings to human neuroimaging.

April 7th 2026

🎉 New paper

March 28th 2026

🎉 New paper

March 18th 2026

💻 Software release

March 2026

2025

🎉 Funding

ERA-NET NEURON funds NEUROFLEX

Our international consortium NEUROFLEX (“The Flexible Mind”) was selected in the ERA-NET NEURON JTC 2025 call on the neuroscience of pain — cognitive flexibility and large-scale brain dynamics as targets for chronic pain.

November 2025

🎉 New paper

DWI brain–behaviour models: replicability paper in Communications Biology

“On the replicability of diffusion weighted MRI-based brain-behavior models” by Raviteja Kotikalapudi et al.

October 30th 2025

💬 Commentary

New commentray on a pain sensitivity biomarker in JAMA Neurology

“Concern About Predictive Performance of a Pain Sensitivity Biomarker” by Ole Goltermann, Tamas Spisak and Christian Büchel

July 21th 2025

🔥 Preprint

New preprint on self-orthogonalizing attractor networks

“Self-orthogonalizing attractor neural networks emerging from the free energy principle” by T. Spisak and K. Friston. Now published in Neurocomputing — see above.

May 28th 2025

🔥 Preprint

Mechanisms of conditioned vs. verbally induced placebo analgesia

“Meta-analytic evidence for distinct neural correlates of conditioned vs. verbally induced placebo analgesia” by T. Spisak et al. Now in Nature Communications — see above.

May 22th 2025

🔥 Preprint

New preprint on common and distinct mechanisms of pain-related learning

“Common and distinct neural mechanisms of aversive and appetitive pain-related learning” by Jialin Li et al.

Apr 3th 2025

✈️ Conference Visit

Meet us on CCN2025 in Amsterdam!

“High-level information integration in the brain via large-scale attractor dynamics” #274

“Towards generative AI-based fMRI paradigms: reinforcement learning via real-time brain feedback” #552 Meet there Tamas and Giuseppe!

August 12-15 2025

🎉 New paper

Our paper about Registered models and adaptive sample splitting is accepted in GigaScience!

External validation of machine learning models - registered models and adaptive sample splitting - by Gallitto et al.

March 15th 2025

2024

🔥 Preprint

New preprint on the replicability of DWI-based predictive models

“On the replicability of diffusion weighted MRI-based brain-behavior models” by Kotikalapudi et al.

July 11th 2024

✈️ Conference Visit

Meet us on IASP2024 in Amsterdam!

Our contributions: Machine Learning Masterclass talk by Tamas Spisak; two posters by Jialin Li and Balint Kincses

July 18th 2024

🔥 New paper

The RCPL-signature paper is out in Comm. Biol.

An externally validated resting-state brain connectivity signature of pain-related learning. Balint Kincses, Katarina Forkmann, Frederik Schlitt, Robert Jan Pawlik, Katharina Schmidt, Dagmar Timmann, Sigrid Elsenbruch, Katja Wiech, Ulrike Bingel & Tamas Spisak

July 17th 2024

🔥 Preprint Alert

Our new preprint about the replicability of DWI-based multivariate BWAS is out!

On the replicability of diffusion weighted MRI-based brain-behavior models, Raviteja Kotikalapudi, Balint Kincses, Giuseppe Gallitto, Robert Englert, Kevin Hoffschlag, Jialin Li, Ulrike Bingel, Tamas Spisak Click for details.

July 11th 2024

✈️ Conference visit

May 20th 2024

🔥 New paper

July 17th 2024

2023

🔥 Preprint Alert

Adaptivesplit preprint out!

External validation of machine learning models - registered models and adaptive sample splitting, Giuseppe Gallitto, Robert Englert, Balint Kincses, Raviteja Kotikalapudi, Jialin Li, Kevin Hoffschlag, Ulrike Bingel, Tamas Spisak Click for details.

May 10th 2023

💻 Software release

The connattractor package for fcHNN analyses is now available on PyPI. Installation and quickstart here.

Nov 21th 2023

🎉 Paper accepted

Nov 9th 2023

🔥 Preprint Alert

The fcHNN preprint is out

Our preprint about functional connectivity-based Hopfield networks is out!
Click for details.

Nov 6th 2023

🌐 New website

The Lab has a new website

Welcome to our new website!
This website is still under construction.
Looking for the old website? Click here!

Nov 6th 2023

References
  1. Englert, R., Kincses, B., Kotikalapudi, R., Gallitto, G., Li, J., Hoffschlag, K., Woo, C.-W., Wager, T. D., Timmann, D., Bingel, U., & Spisak, T. (2026). Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease. eLife, 13. 10.7554/elife.98725
  2. Badrulhisham, F., Pogatzki-Zahn, E., Segelcke, D., Spisak, T., & Vollert, J. (2024). Machine learning and artificial intelligence in neuroscience: A primer for researchers. Brain, Behavior, and Immunity, 115, 470–479. 10.1016/j.bbi.2023.11.005