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News¶
Latest¶
🔥 Preprint
“Beyond pain: a brain-based biomarker predicts individual pain relief” by Jialin Li et al. — a task-fMRI signature that captures both pain exacerbation and relief, validated in chronic back pain.
🔥 Preprint
“Reinforcement Learning via Brain Feedback for real-time fMRI-based adaptive stimulus generation” by Giuseppe Gallitto et al. — closed-loop RL that adapts stimuli from ongoing neural responses. See also our RLBF project page.
🎉 New paper
“Meta-analytic evidence for distinct neural correlates of conditioned versus verbally induced placebo analgesia” by Tamas Spisak, Helena Hartmann et al. & the Placebo Imaging Consortium. Preprint: bioRxiv.
🔥 Preprint
“Layer-specific cortical processing dissociates sensory and cognitive influences on pain” by Balint Kincses et al. — 7T laminar fMRI links middle-layer bottom-up and superficial-layer top-down effects to distraction analgesia. Project page.
🎉 New paper
“Predicting individual differences of fear and cognitive learning and extinction” by Gomes, Bach, Razi, …, Spisak, Axmacher et al.
🔥 Preprint
“Cerebellar activation in human placebo analgesia: Bridging findings from mice to humans” by Zhenjiang Wei et al. — cross-species evidence that the cerebellum is engaged during placebo analgesia, linking rodent findings to human neuroimaging.
🎉 New paper
“Self-orthogonalizing attractor neural networks emerging from the free energy principle” by Tamas Spisak & Karl Friston — a first-principles collaboration now published. Manuscript site · ScienceDirect
🎉 New paper
“Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease” by Robert Englert et al. connattractor · Englert et al. (2026)
💻 Software release
Lightweight package for minimalistic, lightning-fast brain surface visualizations with contour overlay (including cerebellum). pip install from GitHub — see Software.
2025¶
🎉 Funding
Our international consortium NEUROFLEX (“The Flexible Mind”) was selected in the ERA-NET NEURON JTC 2025 call on the neuroscience of pain — cognitive flexibility and large-scale brain dynamics as targets for chronic pain.
🎉 New paper
“On the replicability of diffusion weighted MRI-based brain-behavior models” by Raviteja Kotikalapudi et al.
💬 Commentary
“Concern About Predictive Performance of a Pain Sensitivity Biomarker” by Ole Goltermann, Tamas Spisak and Christian Büchel
🔥 Preprint
“Self-orthogonalizing attractor neural networks emerging from the free energy principle” by T. Spisak and K. Friston. Now published in Neurocomputing — see above.
🔥 Preprint
“Meta-analytic evidence for distinct neural correlates of conditioned vs. verbally induced placebo analgesia” by T. Spisak et al. Now in Nature Communications — see above.
🔥 Preprint
“Common and distinct neural mechanisms of aversive and appetitive pain-related learning” by Jialin Li et al.
✈️ Conference Visit
“High-level information integration in the brain via large-scale attractor dynamics” #274
“Towards generative AI-based fMRI paradigms: reinforcement learning via real-time brain feedback” #552 Meet there Tamas and Giuseppe!
🎉 New paper
External validation of machine learning models - registered models and adaptive sample splitting - by Gallitto et al.
2024¶
🔥 Preprint
“On the replicability of diffusion weighted MRI-based brain-behavior models” by Kotikalapudi et al.
✈️ Conference Visit
Our contributions: Machine Learning Masterclass talk by Tamas Spisak; two posters by Jialin Li and Balint Kincses
🔥 New paper
An externally validated resting-state brain connectivity signature of pain-related learning. Balint Kincses, Katarina Forkmann, Frederik Schlitt, Robert Jan Pawlik, Katharina Schmidt, Dagmar Timmann, Sigrid Elsenbruch, Katja Wiech, Ulrike Bingel & Tamas Spisak
🔥 Preprint Alert
On the replicability of diffusion weighted MRI-based brain-behavior models, Raviteja Kotikalapudi, Balint Kincses, Giuseppe Gallitto, Robert Englert, Kevin Hoffschlag, Jialin Li, Ulrike Bingel, Tamas Spisak Click for details.
✈️ Conference visit
Visit our posters (Jialin Li, Balint Kincses, Raviteja Kotikalapudi, Giuseppe Gallitto, Robert Englert) and see Giuseppe’s talk about reinforcement learning with brain feedback (RLBF) on the last day.
🔥 New paper
It’s an honor to co-author this new paper about: The past, present, and future of the brain imaging data structure (BIDS). See also scientific practices.
2023¶
🔥 Preprint Alert
External validation of machine learning models - registered models and adaptive sample splitting, Giuseppe Gallitto, Robert Englert, Balint Kincses, Raviteja Kotikalapudi, Jialin Li, Kevin Hoffschlag, Ulrike Bingel, Tamas Spisak Click for details.
💻 Software release
The connattractor package for fcHNN analyses is now available on PyPI. Installation and quickstart here.
🎉 Paper accepted
Machine learning and artificial intelligence in neuroscience: A primer for researchers (doi)
🔥 Preprint Alert
Our preprint about functional connectivity-based Hopfield networks is out!
Click for details.
🌐 New website
Welcome to our new website!
This website is still under construction.
Looking for the old website? Click here!
- Englert, R., Kincses, B., Kotikalapudi, R., Gallitto, G., Li, J., Hoffschlag, K., Woo, C.-W., Wager, T. D., Timmann, D., Bingel, U., & Spisak, T. (2026). Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease. eLife, 13. 10.7554/elife.98725
- Badrulhisham, F., Pogatzki-Zahn, E., Segelcke, D., Spisak, T., & Vollert, J. (2024). Machine learning and artificial intelligence in neuroscience: A primer for researchers. Brain, Behavior, and Immunity, 115, 470–479. 10.1016/j.bbi.2023.11.005